Atracurium Impurity 53 CAS 1599467-97-6 (Relative)

Description

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO supplies Atracurium Impurity 53 (CAS 1599467-97-6 (Relative)), a pharmacopoeial impurity reference standard (molecular formula C53H72N2O12C6H5O3S, MW 1086.32 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Atracurium Impurity 53 (C53H72N2O12C6H5O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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